Myelodysplastic syndrome with pure red cell aplasia shows characteristic clinicopathological features and clonal T-cell expansion.

Myelodysplastic syndrome (MDS) is a clonal haematopoietic stem-cell disorder characterised by ineffective haematopoiesis that often exhibits morphological dysplasia and increased erythroid precursors in the bone marrows. MDS with pure red cell aplasia (PRCA) is a rare form of MDS that has been proposed by some to represent a novel and distinct entity {Park et al, 2000; Garcia-Suarez et al, 1998; Williamson et al, 1991). However, the clmicopathological features and underlying pathophysiology of PRCA in the setting of MDS are not well-understood, probably due to the rarity of cases.

作 者：

Wang,SA；Yue,G；Hutchinson,L；Landry,ML；Hasserjian,RP；Hao,S；Galili,N；Raza,A；Woda,BA

刊 名：

British Journal of Haematology 

年，卷(期)：

2007vol.138(no.2) 

分类号：

 

关键词：

Aplastic  Red color  T-Lymphocytes  Myelodysplastic Syndromes  Cells  T淋巴细胞  骨髓增生异常综合征  细胞

正文语种：

eng 

基金项目：