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In this issue, Carrier and colleagues report the period prevalence of cancer in patients with VTE at 3 time points and confirm that unprovoked VTE is more commonly associated with cancer than provoked VTE, and that extensive screening finds more cases of cancer at baseline than usual care. These findings demonstrate that if we look hard enough, we can find hidden cancer in a sizeable proportion of patients with idiopathic VTE. However, the search for cancer is expensive, and we do not know whether finding it changes survival.