Posterior sub-Tenon's triamcinolone injections in the treatment of uveitis.

PURPOSE: This is the first study reported in the United Kingdom to investigate the efficacy and safety of posterior, sub-Tenon's triamcinolone acetonide injections in the treatment of posterior and intermediate uveitis. METHODS: Twenty-eight posterior sub-Tenon's triamcinolone injections (40 mg) were given and the results analysed with a 6 month prospective follow-up in 13 cases. RESULTS: At 6 weeks follow-up, objective improvement in visual acuity occurred in 25 eyes (p < 0.05). Vitreous cellular activity was diminished in 21 eyes (p < 0.05). In most cases improvement was observed within 2 weeks of injection. No patient required repeat triamcinolone injection within 3 months and all patients previously treated with systemic immunosuppression were able to decrease or discontinue this treatment. Complications included transient elevation of intraocular pressure in 4 patients and persistent mild ptosis in 2 patients. CONCLUSIONS: We have demonstrated that posterior sub-Tenon's triamcinolone injection significantly decreases cystoid macular oedema, with a corresponding increase in visual acuity, in patients with posterior uveitis. Systemic immunosuppression may be reduced or discontinued with the avoidance of associated systemic sideeffects, and the technique has a high level of patient acceptability.

作 者：

Tanner,V；Kanski,JJ；Frith,PA

刊 名：

Eye 

年，卷(期)：

1998V.12,no.Pt 4,1998("") 

分类号：

 

关键词：

Anti-Inflammatory Agents, Steroidal  Glucocorticoids, Topical  Triamcinolone  消炎药, 甾类  糖皮质激素类, 外用  曲安西龙  葡萄膜炎, 中间  葡萄膜炎, 后

正文语种：

eng 

基金项目：