学术论文

      味觉敏感性与结肠疾病的相关性研究

      Association between Taste Sensitivity and Conlonic Diseases

      摘要:
      以常熟市各大医院肠镜检查者中的志愿者为受试对象,通过蘸涂法检测其甜味、苦味阈值,结合肠镜检查报告和饮食问卷调查,探讨味觉敏感性与结肠疾病的关系.结果显示,甜味、苦味敏感性均随年龄增长而下降.对所有受试对象进行分析,结肠炎症组与息肉组的苦味阈值较正常组显著增高,而甜味阈值无显著差异;但是炎症组和息肉组的年龄显著大于正常组.进一步分析45~64岁年龄段(组间无年龄差异),结肠炎或息肉患者的甜味阈值显著低于正常组,而苦味阈值没有变化.该研究提示,甜味敏感性高的人群,膳食纤维摄入较少,罹患结肠疾病的风险较高.此外,甜味阈值测试对及早诊治结肠炎或结肠息肉、预防结肠癌的发生以及保护人类健康具有重要价值.
      Abstract:
      People ready to undergo colonoecopy were recruited volenteer as subjects from several major hospitals in Changshu city.Dip-coating method was used to detect the sweet and bitter taste thresholds.The relationship between taste sensitivity and colonic diseases was discussed based on the taste tests,colonoscopy reporting and diet questionnaire.The results showed that sweet,bitter sensitivity were decreased with age.When all subjects were analyzed,the bitterness threshold of colitis and polyp groups was significantly higher than normal group,but the sweetness threshold had no significance;however,the age of colitis and polyp groups was significantly greater than the normal group.Further analysis on the age of 45 ~ 64 years (no age difference among the three groups) showed that,sweetness threshold in colitis or polyps group was significantly lower than the normal group,while the bitterness threshold did not change.It suggests that people with high sweet sensitivity,less dietary fiber intake,have higher the risk of colon disease.In addition,the sweetness threshold test has great value for the early diagnosis and treatment of colitis or colon polyps,colon cancer prevention and the protection of human health.
      作者: 陈梦玲 [1] 朱胜 [2] 朱熙 [1] 朱文杰 [1] 鞠钰蕊 [1] 周心怡 [1] 张根华 [1]
      Author: Chen Mengling [1] Zhu Sheng [2] Zhu Xi [1] Zhu Wenjie [1] Ju Yurui [1] Zhou Xinyi [1] Zhang Genhua [1]
      作者单位: 常熟理工学院生物与食品工程学院,江苏常熟,215500 常熟市第五人民医院,江苏常熟,215500
      年,卷(期): 2017, 40(1)
      分类号: Q189
      在线出版日期: 2017年6月2日
      基金项目: 国家自然科学基金,国家级大学生创新创业训练计划项目(,江苏省第五期“333工程”第三层次培养对象,常熟市医药科技计划项目