The hydrocyclone is affected by the external fluid and can produce vibration, resulting to the changing the distri-bution of internal flows. To study the fluid-solid coupling effect of spiral flow in hydrocyclones under the condition of vibra-tion, the two-directional fluid-structure coupling model with the same vibration frequency is established, where the fluid-structure coupling effect of different exciting forces is simulated. The results show that the spiral flow field moves together with the structure, and the motion of the structure causes the migration of the flow field. The radial velocity of the flow field in the periodic vibration becomes larger, and increases with the increase of the exciting force. The periodic exciting force affects the symmetry of the tangential velocity, and makes the axial velocity near the axial become larger. The trajectory of different cross sections of the structure takes the "O" type, and the vibration shape is parabolic.