学术论文

      中性粒细胞明胶酶相关载脂蛋白在冠心病风险预测中的价值

      Prognostic Value of NGAL in Risk of Coronary Heart Disease

      摘要:
      炎症反应在动脉粥样硬化的发生、发展过程中起着关键作用.近期研究发现新型的炎症标志物中性粒细胞明胶酶相关载脂蛋白在不稳定粥样硬化斑块中表达显著增加,可能对冠心病发病风险具有较好的预测价值,现就二者关系及其机制的研究进展做一综述.
      Abstract:
      The inflammatory response plays a key role in the process of the occurrence and development of atherosclerosis .Neutrophil gelatinase associated lipocalin (NGAL) is a new type of inflammatory biomarker .Recently,elevated NGAL levels have been reported in vul-nerable atherosclerotic plaque ,so it may have a prognostic value for the risk of coronary heart disease .Therefore we performed a review to e-valuate the evidence on the relationship between NGAL and coronary heart disease .Additionally we sought to clarify the mechanism of NGAL in coronary heart disease .
      作者: 刘艳红 刘迎午
      Author: LIU Yanhong LIU Yingwu
      作者单位: 天津市第三中心医院心脏中心,天津,300170
      刊 名: 心血管病学进展 ISTIC
      年,卷(期): 2017, 38(2)
      分类号: R541.4
      在线出版日期: 2017年4月11日