目的 探讨肺部超声评分(LUS)对ICU中普外科术后患者病情严重程度和拔管时机评估的价值,与氧合指数(PaO2/FiO2)、急性生理学与慢性健康状况评分Ⅱ(APACHEⅡ)、序贯器官衰竭评分(SOFA)、住ICU时间及住院时间等的相关性.方法 采用回顾性双盲队列研究的方法,选取ICU中普外科术后成功拔管患者89例,根据患者入住ICU至拔管时间是否大于48 h分为两组:A组为入住ICU至拔管时间小于48 h患者,52例;B组为入住ICU至拔管时间大于48 h患者,37例.患者拔管前检查血气记录PaO2/FiO2,并行APACHEⅡ、SOFA,于拔管前行LUS,记录住ICU时间和总住院时间,并进行相关性分析.结果 A组LUS、APACHEⅡ、SOFA、住ICU时间和总住院时间明显少于B组[(3.98±2.31)分比(13.41±2.82)分、(7.52±1.96)分比(14.92±3.07)分、(4.50±2.24)分比(9.70±3.64)分、(1.77±1.41)d比(8.49±4.35)d和(8.49±2.28)d比(15.63±6.10)d],而PaO2/FiO2明显高于B组[(441.57±45.31)mmHg比(305.78±90.72)mmHg,1 mmHg=0.133 kPa],差异有统计学意义(P<0.01).LUS与PaO2/FiO2呈负相关(r=-0.882,P<0.01),与APACHEⅡ、SOFA、住ICU时间和总住院时间呈正相关(r=0.711、0.590、0.930和0.709,P<0.01).结论 LUS简单易行、安全高效,可以及时评估、有效观察肺部状况,提供临床参考,可用于辅助判断肺部病变严重程度、拔管时机及判断住ICU时间、总住院时间.
Objective To evaluate the value of lung ultrasound score (LUS) on assessing the severity and extubation opportunity in postoperative patients of general surgery, and to investigate the correlation between LUS and oxygenation index (PaO2/FiO2), acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ), sequential organ failure assessment (SOFA), stay length in ICU and stay length in hospital. Methods A prospective double- blind cohort study was conducted. Eighty- nine postoperative patients of general surgery with successful extubation were selected, and the patients were divided into 2 groups:group A ( admission ICU to extubation time less than 48 h, 52 cases) and group B(admission ICU to extubation time more than 48 h, 37 cases). Before extubation, the PaO2/FiO2 was recorded according the blood gas analysis, and APACHE Ⅱ, SOFA and LUS were examined, and the staying time in ICU and staying time in hospital were recorded. The correlation was analyzed. Results The LUS, APACHE Ⅱ, SOFA, staying time in ICU and staying time in hospital in group A were significantly lower than those in group B: (3.98 ± 2.31) scores vs. (13.41 ± 2.82) scores, (7.52 ± 1.96) scores vs. (14.92 ± 3.07) scores, (4.50 ± 2.24) scores vs. (9.70 ± 3.64) scores, (1.77 ± 1.41) d vs. (8.49 ± 4.35) d and (8.49 ± 2.28) d vs. (15.63 ± 6.10) d, and the PaO2/FiO2 was significantly higher than that in group B:(441.57 ± 45.31) mmHg (1 mmHg=0.133 kPa) vs. (305.78 ± 90.72) mmHg, and there were statistical differences (P<0.01). The LUS had negative correlation with the PaO2/FiO2 (r=-0.882, P<0.01), and it had positive correlation with APACHEⅡ, SOFA, staying time in ICU and staying time in hospital (r=0.711, 0.590, 0.930 and 0.709;P<0.01). Conclusions The LUS is simple and easily available. It can evaluate the changes of pulmonary ventilation, and also evaluate its degree of severity and prognosis. It is helpful in the prediction of the extubation time, staying time in ICU and staying time in hospital in patients with general surgery.