学术论文

      磁共振体素内不相干运动扩散加权成像鉴别乳腺良恶性病变的价值

      The clinical value of non coherent diffusion weighted imaging in magnetic resonance body element for differ-entiating benign and malignant breast cancer

      摘要:
      目的:探讨磁共振体素内不相干运动扩散加权成像(IVIM)模型在乳腺良恶性病变鉴别中的应用价值。方法选取行磁共振动态对比增强扫描(DCE-MRI)的乳腺占位病变患者60例,患者在 MRI 扫描前均未行手术或穿刺活检,扫描后经手术或穿刺活检取病灶组织,由病理证实良性病灶39个(良性组),恶性病灶28个(恶性组),对两组病变的 IVIM-DWI 参数(D 值、D*值和 f 值)进行比较,分析 IVIM模型 DWI 参数(D值、D*值和 f 值)诊断乳腺良恶性病变的诊断效能。结果两组病变 IVIM模型 DWI 参数比较,恶性组的 D值为(0.95±0.19)×10-3 s/mm2,显著低于良性组的(1.33±0.25)×10-3 s/mm2(t =3.89,P <0.05);恶性组的 f值为(8.97±2.01)%,显著高于良性组的(7.01±2.13)%(t =3.93,P <0.05),两组病变的 D*值差异无统计学意义(P >0.05);IVIM模型 DWI 参数鉴别乳腺良恶性病变的诊断效能较高。结论 IVIM模型在乳腺良恶性病变鉴别中的诊断效能较高,具有较高的临床应用价值。
      Abstract:
      Objective To explore the application value of non coherent diffusion weighted imaging(IVIM) model in magnetic resonance body element for differentiating benign and malignant breast cancer.Methods Compar-ison of dynamic enhanced magnetic resonance (DCE -MRI)was conducted in 60 patients with breast occupying lesions,all patients were not treated with biopsy or needle biopsy before MRI scan.The lesions were obtained by oper-ation or biopsy after MRI scan,confirmed by pathology,39 benign lesions(benign group),28 malignant lesions(malig-nant group).IVIM-DWI parameters of two lesions group(D value,D* value and F value)were compared,analyzed IVIMDWI model parameters(D value,D* value and F value)diagnostic efficiency of diagnosis of benign and malig-nant breast lesions.Results Compared with two lesions groups,in the IVIM DWI model parameters,the D value of the malignant group was (0.95 ±0.19)×10 -3 s/mm2 ,which was significantly lower than (1.33 ±0.25)×10 -3 s/mm2 of the benign group (t =3.89,P <0.05),the F value of the malignant group was (8.97 ±2.01)%,which was significantly higher than (7.01 ±2.13)% of the benign group (t =3.93,P <0.05),there was no significant differ-ence in D* values between the two groups (P >0.05).IVIM DWI model in differential diagnosis of breast lesions had high diagnostic efficiency.Conclusion IVIMDWI model in the diagnosis of benign and malignant breast cancer is highly effective,and it has high clinical value.
      作者: 王煊
      Author: Wang Xuan
      作者单位: 运城市中心医院影像科, 山西省运城,044000
      刊 名: 中国基层医药 ISTIC
      年,卷(期): 2017, 24(6)
      在线出版日期: 2017年3月29日