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黄斑裂孔第3、4期視網膜内界膜染色舆剥除的前瞻性研究

A prospective study of staining and removal of retinal internal limiting membrane in stages 3 and 4 macular holes

目的 爲了確定用吲哚青綠介導特發性黄斑裂孔第3、4期視網膜内界膜剥除手術的解剖和視覺效果.方法連績研究3~4期特發性黄斑裂孔病人28例28祗眼.所有眼都施行平部玻璃體次全切除術,必要時清除後部玻璃體及任何可見的視網膜前膜.將濃度爲每毫升0.25mg至1.25mg的ICG溶液緩慢地注入到黄斑,待浸漬時停止.内界膜被染色,距黄斑裂孔邊緣1~2個視盤直徑環行剥除内界膜.手術結束時使用12%Perfluoropropane(C3F8)氣體.術後病人需要保持面朝下2周.結果 隨訪時間爲6~14個月,平均9.5個月.14祗眼(50%)為黄斑裂孔第4期,另14祗眼(50%)爲黄斑裂孔第3期.11祗眼(39.3%)爲1年以上的慢性黄斑裂孔.最後隨訪時25祗眼(89.3%)解剖復位,黄斑裂孔閉合.其中21祗眼(75%)黄斑裂孔封閉,另4眼(14.3%)黄斑裂孔變平.18祗眼(64.3%)視力提高兩行或兩行以上.視力平均提高2.6行(範圍2~7行).非慢性裂孔和慢性裂孔分别提高3.4行和1.4行.經統計學處理,兩組間具有顯著性差异(P=0.031).結論 ICG介導視網膜内界膜剥除在封閉特發性黄斑裂孔第3~4期中是很有幫助的.

作 者:
郭坤豪 賀澤烽  
作者单位:
郭坤豪(中國香港中文大學眼科及視覺科學學系及香港眼科醫院;香港瑪麗醫院眼科)
賀澤烽(中國香港東華東院眼科部) 
刊 名:
美中国际眼科杂志  ISTIC
英文刊名:
U.S. CHINESE JOURNAL OF OPHTHALMOLOGY 
年,卷(期):
2001 1(4) 
分类号:
R77 
关键词:
吲哚青綠 知识脉络  内界膜 知识脉络  黄斑裂孔期 知识脉络  Indocyanine green Internal limiting membrane Macular hole Stage 知识脉络 
机标分类号:
R77 R81 
机标关键词:
黄斑裂孔視網膜内界膜染色内界膜剥除前瞻性研究internal limiting membranevisual acuitymacular holepars plana vitrectomyepiretinal membraneindocyanine greenvisual outcome吲哚青綠隨訪解剖次全切除玻璃病人性差异溶液 
基金项目:
 
DOI:
 
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