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视网膜厚度分析仪在糖尿病视网膜病变检测中的价值

Application of retinal thickness analyzer in assessment of retinal thickness in diabetic retinopathy

目的 目的观察视网膜厚度分析仪(retinal thickness analyzer,RTA)在诊断和量化糖尿病视网膜病变(diabetic retinopathy,DRP)中糖尿病黄斑水肿(diabetic macular edema,DME)的应用价值.方法 应用RTA对147只DRP眼进行后极部视网膜厚度分析,并与38只年龄匹配正常对照眼进行比较.分析病程和血糖与RTA检查结果的相关性.结果 1.RTA可发现视网膜的早期亚临床状态下的视网膜增厚.后极部平均厚度(PPAT)和中心凹旁平均厚度(PFAT)与DRP病程呈正相关,可能对早期判断病变发展进程具有提示作用,对预测DME的进展和预后具有重要的参考价值.2.中心凹平均厚度(FAT)与DRP病程相关系数最大,DME的发生是从中心凹周围向中心凹发展.中心凹平均厚度的增加呈现逐渐递增的趋势,它的改变提示病变发展的进程.病程和血糖与FAT呈正相关.3.视网膜平均厚度在早期就开始变化,而最大厚度的变化不敏感,说明DRP开始可能是弥散的病变,晚期会出现局限的高度水肿变化.结论 RTA为观察DRP和DME病程发展、疗效评估提供了一种有价值的手段.

作 者:
张珑俐 陈松 韩梅 赵秉水 崔文志  
作者单位:
300020,天津,天津市眼科医院 
刊 名:
中国实用眼科杂志  ISTIC PKU
英文刊名:
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY 
年,卷(期):
2007 25(6) 
分类号:
R77 
关键词:
糖尿病性视网膜病变 知识脉络  糖尿病黄斑水肿 知识脉络  视网膜厚度分析仪 知识脉络 
机标分类号:
R77 R45 
机标关键词:
视网膜厚度分析仪糖尿病视网膜病变检测应用价值diabetic retinopathyretinal thickness中心凹macular edema后极部亚临床状态最大厚度早期判断血糖相关系数提示作用黄斑水肿疗效评估进程检查结果有价值 
基金项目:
 
DOI:
 
参考文献(14条)
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  11. Oshima Y.Emi K.Yamanishi S Quantitative assessment of macular thickness in normal subjects and patients with diabetic retinopathy by scanning retinal thickness analyzer 1999(1)
  12. 刘早霞.李中秋.杜园园.苏冠方 糖尿病视网膜病变黄斑厚度定量分析 [期刊论文] -中国老年学杂志2003(3)
  13. Fritsche Peter Retinal thickness analysis(RTA) An objective method to assess and quantify the retinal thickness in healthy controls and in diabetics without diabetic retinopathy 2002(6)
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