胰岛β细胞的胰岛素抵抗

1. Da Silva Xavier G.Varadi A.Ainscow WK Regulation of gene expression by glucose in pancreatic beta-cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase 2000
2. Leibiger IB.Leibiger B.Moede T Selective insulin sigualing through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells 2001
3. Aspinwall CA.Lakey JR.Kennedy RT Insulin-stimulated insulin secretion in single pancreatic beta cells 1999
4. Leibiger B.Wahlander K.Berggren PO Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription 2000
5. Leibiger IB.Leibiger B.Berggren PO Insulin feedback action on pancreatic beta-cell function 2002
6. Kulkarni RN.Bruning JC.Winnay JN Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes 1999
7. Tseng YH.Ueki K.Kriauciunas KM Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin 2002
8. Otani K.Kulkarni RN.Baldwin AC Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice 2004
9. Aspinwall CA.Qian WJ.Roper MG Roles of insulin receptor substrate-1,phosphatidylinositol 3-kinase,and release of intracellular Ca2 + stores in insulin-stimulated insulin secretion in beta-cells 2000
10. Kulkarni RN.Roper MG.Dahlgren G Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco (endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3 2004
11. Kulkarni RN.Winnay JN.Daniels M Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines 1999
12. Kubota N.Tobe K.Terauchi Y Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia 2000
13. Hennige AM.Ozcan U.Okada T Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells 2005
14. 邬云红.李秀钧.李宏亮.王煜.张玄娥.柯柳.张祥迅 高脂饮食肥胖大鼠胰岛细胞胰岛素抵抗机理的探讨 [期刊论文] -中华医学杂志2005(27)
15. Ferrannini E.Gastaldelli A.Miyazaki Y Beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes:a new analysis 2005
16. Kahn SE The importance of beta-cell failure in the development and progression of type 2 diabetes 2001
17. 赵家伟.李秀钧 胰岛细胞胰岛素抵抗:2型糖尿病发病机制的主角? [期刊论文] -中华内分泌代谢杂志2004(3)
18. Schwartz MW.Woods SC.Porte D Jr Central nervous system control of food intake 2000
19. Kahn SE The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes 2003

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